Direct synthesis of sensitive selenocysteine peptides by the Ugi reaction.

نویسندگان

  • Muhammad Abbas
  • Ludger A Wessjohann
چکیده

Ammonia and selenoaldehydes are both problematic components in Ugi reactions. Here we report the efficient direct multicomponent synthesis of sensitive selenocysteine peptides without the use of convertible (protected) primary amines, including suitable deprotection protocols for selenols.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 10 47  شماره 

صفحات  -

تاریخ انتشار 2012